Adrenosterone
From Wikipedia
| Adrenosterone | |
|---|---|
(8S,9S,10R,13S,14S)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16- decahydrocyclopenta[a]phenanthrene-3,11,17-trione | |
other names Reichstein's substance G | |
| Identifiers | |
| CAS number | 382-45-6 |
| PubChem | 223997 |
| ChemSpider | 194597 |
| MeSH | Adrenosterone |
| SMILES | O=C4/C=C3/CC[C@@H]2[C@H](C(=O)C[C@@]1(C(=O)CC[C@H]12)C)[C@@]3(C)CC4 |
| InChI | 1/C19H24O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-14,17H,3-8,10H2,1-2H3/t13-,14-,17+,18-,19-/m0/s1 |
| InChI key | RZRPTBIGEANTGU-IRIMSJTPBG |
| Properties | |
| Molecular formula | C19H24O3 |
| Molar mass | 300.39 g/mol |
| Melting point | 222°C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Adrenosterone is a steroid hormone with weak androgenic effect. It was first isolated in 1936 from the adrenal cortex by Tadeus Reichstein at the Pharmaceutical Institute in the University of Basel. Originally, adrenosterone was called Reichstein's substance G. Adrenosterone occurs in humans as well as most mammals and is the primary androgenic precursor in fish.[citation needed]
Adrenosterone is sold as a dietary supplement since 2007 under the trade name 11-OXO. It is a selective 11β-HSD inhibitor.[citation needed]
11-Keto-androstenedione or 11-keto-androstenetrione are also trade names for this hormone, while the correct name would be androst-4-ene-3,11,17-trione.
References
| This article does not cite any references or sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (October 2009) |
See also
| This biochemistry article is a stub. You can help Wikipedia by expanding it. |
Boggle


