» 
Arabic Bulgarian Chinese Croatian Czech Danish Dutch English Estonian Finnish French German Greek Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Korean Latvian Lithuanian Malagasy Norwegian Persian Polish Portuguese Romanian Russian Serbian Slovak Slovenian Spanish Swedish Thai Turkish Vietnamese
Arabic Bulgarian Chinese Croatian Czech Danish Dutch English Estonian Finnish French German Greek Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Korean Latvian Lithuanian Malagasy Norwegian Persian Polish Portuguese Romanian Russian Serbian Slovak Slovenian Spanish Swedish Thai Turkish Vietnamese

definitions - Chloroform

chloroform (n.)

1.(medicine)a volatile liquid haloform (CHCl3); formerly used as an anesthetic"chloroform was the first inhalation anesthetic"

chloroform (v.)

1.anesthetize with chloroform"Doctors used to put people under by chloroforming them"

Chloroform (n.)

1.(MeSH)A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.

   Advertizing ▼

Merriam Webster

ChloroformChlo"ro*form (?), n. [Chlorine + formyl, it having been regarded as a trichloride of this radical: cf. F. chloroforme, G. chloroform.] (Chem.) A colorless volatile liquid, CHCl3, having an ethereal odor and a sweetish taste, formed by treating alcohol with chlorine and an alkali. It is a powerful solvent of wax, resin, etc., and is extensively used to produce anæsthesia in surgical operations; also externally, to alleviate pain.

ChloroformChlo"ro*form (?), v. t. [imp. & p. p. Chloroformed (?); p. pr. & vb. n. Chloroforming.] To treat with chloroform, or to place under its influence.

   Advertizing ▼

definition (more)

definition of Wikipedia

synonyms - Chloroform

Chloroform (n.) (MeSH)

Trichloromethane  (MeSH)

chloroform (n.) (medicine)

trichloromethane

phrases

analogical dictionary





Wikipedia

Chloroform

                   
Chloroform
Identifiers
CAS number 67-66-3 YesY
PubChem 6212
ChemSpider 5977 YesY
UNII 7V31YC746X YesY
EC number 200-663-8
KEGG C13827 YesY
ChEBI CHEBI:35255 YesY
ChEMBL CHEMBL44618 YesY
RTECS number FS9100000
Jmol-3D images Image 1
Properties
Molecular formula CHCl3
Molar mass 119.38 g mol−1
Appearance Colorless liquid
Density 1.483 g/cm3
Melting point

-63.5 °C, 210 K, -82 °F

Boiling point

61.2 °C, 334 K, 142 °F

Solubility in water 0.8 g/100 mL (20 °C)
Refractive index (nD) 1.4459
Structure
Molecular shape Tetrahedral
Hazards
MSDS External MSDS
R-phrases R22, R38, R40, R48/20/22
S-phrases (S2), S36/37
Main hazards Harmful (Xn), Irritant (Xi), Carc. Cat. 2B
NFPA 704
NFPA 704.svg
0
2
0
Flash point Non-flammable
U.S. Permissible
exposure limit (PEL)
50 ppm (240 mg/m3) (OSHA)
Supplementary data page
Structure and
properties
n, εr, etc.
Thermodynamic
data
Phase behaviour
Solid, liquid, gas
Spectral data UV, IR, NMR, MS
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references
  Chloroform in its liquid state shown in a test tube

Chloroform is an organic compound with formula CHCl3. It is one of the four chloromethanes.[1] The colorless, sweet-smelling, dense liquid is a trihalomethane, and is considered somewhat hazardous. Several million tons are produced annually as a precursor to Teflon and refrigerants, but its use for refrigerants is being phased out.[1]

Contents

  Occurrence

Chloroform has a multitude of natural sources, both biogenic and abiotic. It is estimated that greater than 90% of atmospheric chloroform is of natural origin.[2]

  Marine

In particular, chloroform is produced by brown seaweeds (Laminaria digitata, Laminaria saccharina, Fucus serratus, Pelvetia canaliculata, Ascophyllum nodosum), red seaweeds (Gigartina stellata, Corallina officinalis, Polysiphonia lanosa), and green seaweeds (Ulva lactuca, Enteromorpha sp., Cladophora albida).[3] Similarly, the macroalga Eucheuma denticulatum, which is cultivated and harvested on a large scale for carrageenan production, produces chloroform,[4] as do Hypnea spinella, Falkenbergia hillebrandii, and Gracilara cornea along with seven indigenous macroalgae inhabiting a rock pool.[5] These studies show increased chloroform production with increased light intensity, presumably when photosynthesis is at a maximum. Chloroform is also produced by the brown algae Fucus vesiculosus, the green algae Cladophora glomerata, Enteromorpha ahlneriana, Enteromorpha flexuosa, and Enteromorpha intestinalis, and the diatom Pleurosira laevis.[6] Other studies observe chloroform in Fucus serratus, Corallina officinalis, Cladophora pellucida, and Ulva lactuca,[7] and Desmarestia antarctica, Lambia antarctica, Laminaria saccharina, Neuroglossum ligulatum.[8]

  Production

Chloroform was discovered by three researchers independently of one another. Chloroform was reported in 1831 by the French chemist Eugène Soubeiran, who prepared it from acetone (2-propanone) as well as ethanol through the action of chlorine bleach powder (calcium hypochlorite).[9] The American physician Samuel Guthrie prepared gallons of the material and described its "deliciousness of flavor."[10] Independently, Justus von Liebig also described the same compound.[11] All early preparations used variations of the haloform reaction. Chloroform was named and chemically characterized in 1834 by Jean-Baptiste Dumas.[12]

  Industrial routes

In industry, chloroform is produced by heating a mixture of chlorine and either chloromethane or methane.[1] At 400–500 °C, a free radical halogenation occurs, converting these precursors to progressively more chlorinated compounds:

CH4 + Cl2 → CH3Cl + HCl
CH3Cl + Cl2CH2Cl2 + HCl
CH2Cl2 + Cl2 → CHCl3 + HCl

Chloroform undergoes further chlorination to yield carbon tetrachloride (CCl4):

CHCl3 + Cl2 → CCl4 + HCl

The output of this process is a mixture of the four chloromethanes (chloromethane, dichloromethane, chloroform, and carbon tetrachloride), which can then be separated by distillation.[1]

  Deuterochloroform

Deuterated chloroform is an isotopologue of chloroform with a single deuterium atom. CDCl3 is a common solvent used in NMR Spectroscopy. Deuterochloroform is produced by the haloform reaction[citation needed], the reaction of acetone (or ethanol) with sodium hypochlorite or calcium hypochlorite.[1] The haloform process is now obsolete for the production of ordinary chloroform. Deuterochloroform can also be prepared by the reaction of sodium deuteroxide with chloral hydrate,[citation needed] or from ordinary chloroform.[13]

  Inadvertent formation of chloroform

The haloform reaction can also occur inadvertently in domestic settings.[citation needed] Sodium hypochlorite solution (chlorine bleach) mixed with common household liquids such as acetone, butanone, ethanol, or isopropyl alcohol can produce some chloroform, in addition to other compounds such as chloroacetone or dichloroacetone.[citation needed]

  Uses

The major use of chloroform today is in the production of the chlorodifluoromethane (R-22), a major precursor to tetrafluoroethylene:

CHCl3 + 2 HF → CHClF2 + 2 HCl

The reaction is conducted in the presence of a catalytic amount of antimony pentafluoride. Chlorodifluoromethane is then converted into tetrafluoroethylene, the main precursor to Teflon. Before the Montreal Protocol, chlorodifluoromethane (R22) was also a popular refrigerant.

  As a solvent

Chloroform is a common solvent in the laboratory because it is relatively unreactive, miscible with most organic liquids, and conveniently volatile. Chloroform is used as a solvent in the pharmaceutical industry and for producing dyes and pesticides. Chloroform is an effective solvent for alkaloids in their base form and thus plant material is commonly extracted with chloroform for pharmaceutical processing. For example, it is used in commerce to extract morphine from poppies and scopolamine from Datura plants.

It can be used to bond pieces of acrylic glass (also known under the trade names Perspex and Plexiglas).

A solvent of phenol:chloroform:isoamyl alcohol 25:24:1 is used to dissolve non-nucleic acid biomolecules in DNA and RNA extractions.

Chloroform containing deuterium (heavy hydrogen), CDCl3, is a common solvent used in NMR spectroscopy.

  As a reagent in organic synthesis

As a reagent, chloroform serves as a source of the dichlorocarbene CCl2 group.[14] It reacts with aqueous sodium hydroxide usually in the presence of a phase transfer catalyst to produce dichlorocarbene, CCl2.[15][16] This reagent affects ortho-formylation of activated aromatic rings such as phenols, producing aryl aldehydes in a reaction known as the Reimer-Tiemann reaction. Alternatively the carbene can be trapped by an alkene to form a cyclopropane derivative. In the Kharasch addition chloroform forms the CHCl2 free radical in addition to alkenes.

  As an anesthetic

  Antique bottles of Chloroform

Chloroform was once a widely used anesthetic. Its vapor depresses the central nervous system of a patient, allowing a doctor to perform various otherwise painful procedures. On 4 November 1847, the Scottish obstetrician James Young Simpson discovered the anaethestic qualities of chloroform when he and his friends were experimenting with different substances on themselves in search of a replacement for ether as a general anesthesia. He was so astounded by the success of his own trial that the next morning he hired a chemist and within the next few days was administering it to his patients during childbirth.[17] The use of chloroform during surgery expanded rapidly thereafter in Europe. In the 1850s, chloroform was used during the birth of Queen Victoria's last two children.[18] In the United States, chloroform began to replace ether as an anesthetic at the beginning of the 20th century; however, it was quickly abandoned in favor of ether upon discovery of its toxicity, especially its tendency to cause fatal cardiac arrhythmia analogous to what is now termed "sudden sniffer's death". Ether is still the preferred anesthetic in some developing nations due to its high therapeutic index, and low price. One possible mechanism of action for chloroform is that it increases movement of potassium ions through certain types of potassium channels in nerve cells.[19] Chloroform could also be mixed with other anaesthetic agents such as ether to make C.E. mixture, or ether and alcohol to make A.C.E. mixture.

Chloroform has been used by criminals to knock out, daze or even murder their victims. Joseph Harris was charged with using chloroform in 1894 to rob people.[20] Chloroform was used to murder a woman in 1991 as a toxic dose was delivered while she was sleeping.[21] In 2007 a man was convicted of using chloroform to sexually assault minors.[22][23]

  Safety

Fatal oral dose of chloroform may be as low as 10 mL (14.8 g), with death due to respiratory or cardiac arrest.[24]

As might be expected for an anesthetic, chloroform vapors depress the central nervous system. It is immediately dangerous to life and health at approximately 500 ppm, according to the U.S. National Institute for Occupational Safety and Health. Breathing about 900 ppm for a short time can cause dizziness, fatigue, and headache. Chronic chloroform exposure can damage the liver (where chloroform is metabolized to phosgene) and the kidneys, and some people develop sores when the skin is immersed in chloroform.

Animal studies have shown that miscarriages occur in rats and mice that have breathed air containing 30 to 300 ppm of chloroform during pregnancy and also in rats that have ingested chloroform during pregnancy. Offspring of rats and mice that breathed chloroform during pregnancy have a higher incidence of birth defects, and abnormal sperm have been found in male mice that have breathed air containing 400 ppm chloroform for a few days. The effect of chloroform on reproduction in humans is unknown.

Chloroform once appeared in toothpastes, cough syrups, ointments, and other pharmaceuticals, but it has been banned as a consumer product in the US since 1976.[25] Cough syrups containing chloroform can still be legally purchased in pharmacies and supermarkets in the UK.

The US National Toxicology Program's twelfth report on carcinogens[26] implicates it as reasonably anticipated to be a human carcinogen, a designation equivalent to International Agency for Research on Cancer class 2A. The IARC itself classifies chloroform as possibly carcinogenic to humans, a Group 2B designation.[27] It has been most readily associated with hepatocellular carcinoma.[28][29] Caution is mandated during its handling in order to minimize unnecessary exposure; safer alternatives, such as dichloromethane, have resulted in a substantial reduction of its use as a solvent.

Hannah Greener, a 14 year old girl who was having an infected toenail removed, died almost immediately after being given the anesthetic. Chloroform affected the heart and a number of young, physically fit patients died after inhaling it. However, in 1848 John Snow developed an inhaler that regulated the dosage and so successfully reduced the number of deaths.

  Conversion to phosgene

During prolonged storage in the presence of oxygen chloroform converts slowly to phosgene. To prevent accidents, commercial chloroform is stabilized with ethanol or amylene, but samples that have been recovered or dried no longer contain any stabilizer. Amylene has been found ineffective, and the phosgene can affect analytes in samples, lipids, and nucleic acids dissolved in or extracted with chloroform.[30] Dissolved phosgene cannot be removed by distillation or carbon filters, but it is removed by calcium hydroxide or activated alumina.[31]

Suspected samples can be tested for phosgene using filter paper (treated with 5% diphenylamine, 5% dimethylaminobenzaldehyde in alcohol, and then dried), which turns yellow in phosgene vapor. There are several colorimetric and fluorometric reagents for phosgene, and it can also be quantified with mass spectrometry.

  References

  1. ^ a b c d e M. Rossberg et al. “Chlorinated Hydrocarbons” in Ullmann’s Encyclopedia of Industrial Chemistry, 2006, Wiley-VCH, Weinheim. doi:10.1002/14356007.a06_233.pub2
  2. ^ http://www.eurochlor.org/upload/documents/document56.pdf
  3. ^ Nightingale PB, Malin G, Liss PS (1995). "Production of Chloroform and Other Low- Molecular-Weight Halocarbons by Some Species of Macroalgae". Limnology and Oceanography (American Society of Limnology and Oceanography) 40 (4): 680. JSTOR 2838303. 
  4. ^ Mtolera, Matern; Collén, Jonas; Pedersén, Marianne; Ekdahl, Anja; Abrahamsson, Katarina; Semesi, Adelaida (1996). "Stress-induced production of volatile halogenated organic compounds in Eucheuma denticulatum (Rhodophyta) caused by elevated pH and high light intensities". European Journal of Phycology 31 (1): 89. DOI:10.1080/09670269600651241. 
  5. ^ Ekdahl A, Pedersen M, Abrahamsson K (1998). "A Study of the Diurnal Variation of Biogenic Volatile Halocarbons". Mar Chem 63: 1. 
  6. ^ Abrahamsson, K; Choo, KS; Pedersén, M; Johansson, G; Snoeijs, P (2003). "Effects of temperature on the production of hydrogen peroxide and volatile halocarbons by brackish-water algae.". Phytochemistry 64 (3): 725–34. DOI:10.1016/S0031-9422(03)00419-9. PMID 13679095. 
  7. ^ Baker JM, Sturges WT, Sugier J, Sunnenberg G, Lovett AA, Reeves CE, Nightingale PD, Penkett SA (2001). "Emissions of CH3Br, Organochlorines, and Organoiodines from Temperate Macroalgae". Chemosphere - Global Change Science 3 (1): 93. DOI:10.1016/S1465-9972(00)00021-0. 
  8. ^ Laturnus, F; Svensson, T; Wiencke, C; Oberg, G (2004). "Ultraviolet radiation affects emission of ozone-depleting substances by marine macroalgae: results from a laboratory incubation study.". Environmental Science & Technology 38 (24): 6605–9. DOI:10.1021/es049527s. PMID 15669318. 
  9. ^ Eugène Soubeiran (1831). Ann. Chim. 48: 131. 
  10. ^ Samuel Guthrie (1832). "New mode of preparing a spirituous solution of Chloric Ether". Am. J. Sci. And Arts 21: 64. 
  11. ^ Justus Liebig (1832). "Ueber die Verbindungen, welche durch die Einwirkung des Chlors auf Alkohol, Aether, ölbildendes Gas und Essiggeist entstehen". Annalen der Pharmacie 1 (2): 182–230. DOI:10.1002/jlac.18320010203. 
  12. ^ Jean-Baptiste Dumas (1834). "Untersuchung über die Wirkung des Chlors auf den Alkohol". Annalen der Pharmacie 107 (41): 650–656. DOI:10.1002/andp.18341074103. 
  13. ^ Canadian Patent 1085423
  14. ^ Srebnik, M.; Laloë, E. "Chloroform" Encyclopedia of Reagents for Organic Synthesis" 2001 John Wiley.doi:10.1002/047084289X.rc105
  15. ^ "1,6-Methano[10]annulene", Org. Synth., 1988, http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv6p0731 ; Coll. Vol. 6: 731 
  16. ^ Gokel, G. W.; Widera, R. P.; Weber, W. P. (1988), "Phase-Transfer Hofmann Carbylamine Reaction: tert-Butyl Isocyanide", Org. Synth., http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv6p0232 ; Coll. Vol. 6: 232 
  17. ^ Gordon, H. Laing (2002-11). Sir James Young Simpson and Chloroform (1811-1870). The Minerva Group, Inc.. pp. 106–109. ISBN 978-1-4102-0291-8. http://books.google.com/books?id=pYer05UwKBYC&pg=PA106. Retrieved 11 November 2011. 
  18. ^ Anesthesia and Queen Victoria
  19. ^ Patel, Amanda J.; Honoré, Eric; Lesage, Florian; Fink, Michel; Romey, Georges; Lazdunski, Michel (May 1999). "Inhalational anesthetics activate two-pore-domain background K+ channels". Nature Neuroscience 2 (5): 422–426. DOI:10.1038/8084. PMID 10321245. 
  20. ^ "Knock-out and Chloroform". The Philadelphia record. 9 February 1894. http://news.google.com/newspapers?id=Ec1VAAAAIBAJ&sjid=sEANAAAAIBAJ&pg=2904,2720400&dq=chloroform+knockout&hl=en. Retrieved 31 March 2011. 
  21. ^ "Chloroform case retrial underway". Record-Journal. 7 July 1993. http://news.google.com/newspapers?id=I91HAAAAIBAJ&sjid=4f8MAAAAIBAJ&pg=2367,1007950&dq=chloroform+knockout&hl=en. Retrieved 31 March 2011. 
  22. ^ "Man Uses Chloroform In Sex Attacks Of Teens". News 5. 6 November 2007. http://www.wlwt.com/news/14519857/detail.html. Retrieved 31 March 2011. 
  23. ^ "Man admits to raping friends' daughters". USA Today. 6 November 2007. http://www.usatoday.com/news/nation/2007-11-06-chloroform-rapes_N.htm. Retrieved 31 March 2011. 
  24. ^ Chloroform, US Environmental Potection Agency
  25. ^ "The National Toxicology Program: Substance Profiles: Chloroform CAS No. 67-66-3" (pdf). http://ntp.niehs.nih.gov/ntp/roc/twelfth/profiles/Chloroform.pdf. Retrieved 2012-05-21. 
  26. ^ "Substances Listed in the Twelfth Report on Carcinogens" (pdf). http://ntp.niehs.nih.gov/ntp/roc/twelfth/ListedSubstancesReasonablyAnticipated.pdf. Retrieved 2012-05-21. 
  27. ^ "International Agency for Research on Cancer (IARC) - Summaries & Evaluations: Chloroform". http://www.inchem.org/documents/iarc/vol73/73-05.html. Retrieved 2010-09-02. 
  28. ^ "Centers for Disease Control and Prevention: Current Intelligence Bulletin 9". http://www.cdc.gov/niosh/docs/1970/78127_9.html. 
  29. ^ "National Toxicology Program: Report on the carcinogenesis bioassay of chloroform". http://ntp.niehs.nih.gov/ntp/htdocs/LT_rpts/trChloroform.pdf. 
  30. ^ (Turk, Eric, "Phosgene from Chloroform", Chemical & Engineering News (2 March 1998) Vol. 76, No. 9, pp. 6.)
  31. ^ (Cone, Edward J., William F. Buckwald, and William D. Darwin, "Analytical controls in Drug Metabolic Studies, II Artifact formation During Chloroform Extraction of Drugs and Metabolites with Amine Substituents",Drug Metabolism & Disposition November 1982 vol. 10 no. 6 561-567)

  External links

   
               

 

All translations of Chloroform


sensagent's content

  • definitions
  • synonyms
  • antonyms
  • encyclopedia

Dictionary and translator for handheld

⇨ New : sensagent is now available on your handheld

   Advertising ▼

sensagent's office

Shortkey or widget. Free.

Windows Shortkey: sensagent. Free.

Vista Widget : sensagent. Free.

Webmaster Solution

Alexandria

A windows (pop-into) of information (full-content of Sensagent) triggered by double-clicking any word on your webpage. Give contextual explanation and translation from your sites !

Try here  or   get the code

SensagentBox

With a SensagentBox, visitors to your site can access reliable information on over 5 million pages provided by Sensagent.com. Choose the design that fits your site.

Business solution

Improve your site content

Add new content to your site from Sensagent by XML.

Crawl products or adds

Get XML access to reach the best products.

Index images and define metadata

Get XML access to fix the meaning of your metadata.


Please, email us to describe your idea.

WordGame

The English word games are:
○   Anagrams
○   Wildcard, crossword
○   Lettris
○   Boggle.

Lettris

Lettris is a curious tetris-clone game where all the bricks have the same square shape but different content. Each square carries a letter. To make squares disappear and save space for other squares you have to assemble English words (left, right, up, down) from the falling squares.

boggle

Boggle gives you 3 minutes to find as many words (3 letters or more) as you can in a grid of 16 letters. You can also try the grid of 16 letters. Letters must be adjacent and longer words score better. See if you can get into the grid Hall of Fame !

English dictionary
Main references

Most English definitions are provided by WordNet .
English thesaurus is mainly derived from The Integral Dictionary (TID).
English Encyclopedia is licensed by Wikipedia (GNU).

Copyrights

The wordgames anagrams, crossword, Lettris and Boggle are provided by Memodata.
The web service Alexandria is granted from Memodata for the Ebay search.
The SensagentBox are offered by sensAgent.

Translation

Change the target language to find translations.
Tips: browse the semantic fields (see From ideas to words) in two languages to learn more.

last searches on the dictionary :

6034 online visitors

computed in 0.062s

I would like to report:
section :
a spelling or a grammatical mistake
an offensive content(racist, pornographic, injurious, etc.)
a copyright violation
an error
a missing statement
other
please precise:

Advertize

Partnership

Company informations

My account

login

registration

   Advertising ▼

Chloroform (Trichloromethane), 99.9% (HPLC Grade), Certified, 30ml (15.95 USD)

Commercial use of this term

Chloroform (Trichloromethane), ACS, 99.9%, Certified, 500ml x 2 (64.95 USD)

Commercial use of this term

NC-0217 Chloroform, 16oz, Reagent ACS, Solvent, Bonds acrylics (32.95 USD)

Commercial use of this term

Chloroform (Trichloromethane), 99.9% (HPLC Grade), Certified, 100ml (32.95 USD)

Commercial use of this term

Chloroform (Trichloromethane), 99.9% (HPLC Grade), Certified, 500ml (51.95 USD)

Commercial use of this term

Chloroform, 32oz, Reagent ACS, Solvent, Bonds acrylics (53.95 USD)

Commercial use of this term

Chloroform (Trichloromethane), ACS, 99.9%, Certified, 500ml x 4 (111.95 USD)

Commercial use of this term

Chloroform Reagent, ACS Stabiliser 500 ml (GFS Chemical) #3777 (39.95 USD)

Commercial use of this term

Vintage Chloroform Bottle Drugist pharmaceutical Pharmacy Apothocary Poison (15.0 USD)

Commercial use of this term

What a Blessing She Had Chloroform: The Medical and Social Response to the Pain (28.95 USD)

Commercial use of this term

Funny " Chloroform " Biker Patch (5.5 USD)

Commercial use of this term

WHIRR/NOTHING - Ease/Chloroform - LP (18.1 GBP)

Commercial use of this term

ONE MINUTE COUGH CURE E.C.DEWITT CHICAGO 1890s OPIUM & CHLOROFORM BOTTLE (24.0 USD)

Commercial use of this term

***L@@K NEWEST PISO'S "CURE" FOR CONSUMPTION COUGHS COLD CHLOROFORM WARREN PA (27.0 USD)

Commercial use of this term

Medicine medical DRIP by DROP chloroform (Pharmacy, Apothecary) poison bottle! (9.99 USD)

Commercial use of this term

On Chloroform and Other Anaesthetics Their Action and Administration John Snow (21.9 USD)

Commercial use of this term

Labeled Chloroform "Dr Hobsons Compound Syrup Handtooled (45.0 USD)

Commercial use of this term

DOES THIS RAG SMELL Like CHLOROFORM FUN New Club Motorcycle Biker Patch PAT-3247 (3.96 USD)

Commercial use of this term