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definitions - Cyclofenil

Cyclofenil (n.)

1.(MeSH)A gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is thought to be less effective than CLOMIPHENE.

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synonyms - Cyclofenil

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analogical dictionary

 

Carbol, Phenols[Hyper.]

Cresols[Hyper.]

Cyclofenil (n.) [MeSH]


Wikipedia

Cyclofenil

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Cyclofenil
Systematic (IUPAC) name
[4-[(4-acetoxyphenyl)-cyclohexylidene-methyl]phenyl] acetate
Identifiers
CAS number5189-40-2
ATC codeG03GB01
PubChem2898
ChemSpider2795
Chemical data
FormulaC23H24O4 
Mol. mass364.434 g/mol
SMILESeMolecules & PubChem
Synonymsbis(p-acetoxyphenyl)cyclohexylidenemethane
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half life ?
Excretion ?
Therapeutic considerations
Pregnancy cat. ?
Legal status
RoutesOral


Cyclofenil (INN, trade names Ondogyne, Sexovid, and others) is a selective estrogen receptor modulator.

It was investigated as a possible treatment for scleroderma in the 1980s, but was found to be ineffective.[1] Later study of its efficacy in treating Raynaud's phenomenon in people with scleroderma also found no statistically significant benefit.[2]

References

  1. ^ Torres MA, Furst DE (February 1990). [Expression error: Missing operand for > "Treatment of generalized systemic sclerosis"]. Rheum Dis Clin North Am 16 (1): 217–41. PMID 2406809. 
  2. ^ Pope J, Fenlon D, Thompson A, et al. (2000). [Expression error: Missing operand for > "Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis"]. Cochrane Database Syst Rev (2): CD000955. doi:10.1002/14651858.CD000955. PMID 10796397. 


 

All translations of Cyclofenil


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