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Flutoprazepam (Restas, KB-509) is a drug which is a benzodiazepine derivative. It was invented in Japan in 1972, and its medical use remains mostly confined to that country. Its muscle relaxant properties are approximately equivalent to those of diazepam - however, it has more powerful sedative, hypnotic, anxiolytic and anticonvulsant effects and is around four times more potent by weight compared to diazepam.  It is longer acting than diazepam due to its long-acting active metabolites, which contribute significantly to its effects.
Flutoprazepam is typically used for the treatment of severe insomnia and may also be used for treating stomach ulcers.
Abuse of benzodiazepines in Japan is extremely common, with flutoprazepam being one of the most commonly abused, along with the benzodiazepines of abuse nimetazepam, temazepam and triazolam.
Flutoprazepam is currently a Schedule IV drug under the international Convention on Psychotropic Substances of 1971.
In Singapore, flutoprazepam is a Class C-Schedule II drug under the Misuse of Drugs Act.
In Hong Kong, flutoprazepam is regulated under Schedule 2 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. Flutoprazepam may be prescribed for the treatment of insomnia by a registered medical doctor. The penalty for trafficking or manufacturing the substance is a $100,000 (HKD) fine and possibly a short imprisonment (1-2 years). Possession of the substance for consumption without valid prescription from a registered medical doctor is illegal and punishable with a $50,000 (HKD) fine.
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- ^ "Bilingual Laws Information System" (English). The Government of the Hong Kong Special Administrative Region of the People's Republic of China. http://www.legislation.gov.hk/eng/index.htm.