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BoggleGPRC5A
From Wikipedia, the free encyclopedia
| edit |
| G protein-coupled receptor, family C, group 5, member A | |||||||||||
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| Identifiers | |||||||||||
| Symbols | GPRC5A; GPCR5A; RAI3; RAIG1 | ||||||||||
| External IDs | OMIM: 604138 MGI: 1891250 HomoloGene: 2961 IUPHAR: RAIG1 GeneCards: GPRC5A Gene | ||||||||||
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| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 9052 | 232431 | |||||||||
| Ensembl | ENSG00000013588 | ENSMUSG00000046733 | |||||||||
| UniProt | Q8NFJ5 | Q8BHL4 | |||||||||
| RefSeq (mRNA) | NM_003979 | NM_181444 | |||||||||
| RefSeq (protein) | NP_003970 | NP_852109 | |||||||||
| Location (UCSC) | Chr 12: 12.93 - 12.96 Mb | Chr 6: 135.03 - 135.05 Mb | |||||||||
| PubMed search | [1] | [2] | |||||||||
Retinoic acid-induced protein 3 is a protein that in humans is encoded by the GPRC5A gene.[1][2]
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.[2]
Contents |
See also
References
- ^ Cheng Y, Lotan R (Feb 1999). [Expression error: Missing operand for > "Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor"]. J Biol Chem 273 (52): 35008-15. PMID 9857033.
- ^ a b "Entrez Gene: GPRC5A G protein-coupled receptor, family C, group 5, member A". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9052.
External links
- "GPRC5 Receptors: RAIG1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2959.
Further reading
- Cafferata EG, Gonzalez-Guerrico AM, Pivetta OH, Santa-Coloma TA (1997). [Expression error: Missing operand for > "Identification by differential display of a mRNA specifically induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells."]. Cell. Mol. Biol. (Noisy-le-grand) 42 (5): 797–804. PMID 8832110.
- Bräuner-Osborne H, Krogsgaard-Larsen P (2000). [Expression error: Missing operand for > "Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain."]. Genomics 65 (2): 121–8. doi:. PMID 10783259.
- Robbins MJ, Michalovich D, Hill J, et al. (2001). [Expression error: Missing operand for > "Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C)."]. Genomics 67 (1): 8–18. doi:. PMID 10945465.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). [Expression error: Missing operand for > "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."]. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). [Expression error: Missing operand for > "Complete sequencing and characterization of 21,243 full-length human cDNAs."]. Nat. Genet. 36 (1): 40–5. doi:. PMID 14702039.
- Tao Q, Cheng Y, Clifford J, Lotan R (2004). [Expression error: Missing operand for > "Characterization of the murine orphan G-protein-coupled receptor gene Rai3 and its regulation by retinoic acid."]. Genomics 83 (2): 270–80. doi:. PMID 14706456.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). [Expression error: Missing operand for > "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."]. Genome Res. 14 (10B): 2121–7. doi:. PMID 15489334.
- Wu Q, Ding W, Mirza A, et al. (2005). [Expression error: Missing operand for > "Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target."]. J. Biol. Chem. 280 (13): 12935–43. doi:. PMID 15659406.
- Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). [Expression error: Missing operand for > "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules."]. Mol. Cell Proteomics 4 (9): 1240–50. doi:. PMID 15951569.
- Nousiainen M, Silljé HH, Sauer G, et al. (2006). [Expression error: Missing operand for > "Phosphoproteome analysis of the human mitotic spindle."]. Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:. PMID 16565220.
- Hirano M, Zang L, Oka T, et al. (2006). [Expression error: Missing operand for > "Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression."]. Biochem. Biophys. Res. Commun. 351 (1): 185–91. doi:. PMID 17055459.
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