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definitions
MALDI (n.)
1.(MeSH)A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.;A technique incorporating MALDI that uses ultraviolet absorbing organic molecules (matrix) to transfer energy from a LASERS to an analyte for desorption and ionization. It is useful for PROTEIN ARRAY ANALYSIS.
synonyms
MALDI (n.) (MeSH)
E05.196.566.755, Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted (MeSH), MALDI-MS (MeSH), MALD-MS (MeSH), Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization (MeSH), Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization (MeSH), Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry (MeSH), MS-MALD (MeSH), SELDI-TOF-MS (MeSH), Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization (MeSH), Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization (MeSH), Surface Enhanced Laser Desorption Ionization Mass Spectrometry (MeSH)
phrases
analogical dictionary
MALDI (n.)
[MeSH]
