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Wikipedia

Prolactin-releasing peptide receptor

From Wikipedia, the free encyclopedia

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Prolactin releasing hormone receptor
Identifiers
SymbolsPRLHR; GPR10; GR3; MGC126539; MGC126541; PrRPR
External IDsOMIM: 600895 MGI: 2135956 HomoloGene: 3134 IUPHAR: PRRP GeneCards: PRLHR Gene
Orthologs
SpeciesHumanMouse
Entrez2834226278
EnsemblENSG00000119973ENSMUSG00000045052
UniProtP49683Q059H6
RefSeq (mRNA)NM_004248NM_201615
RefSeq (protein)NP_004239NP_963909
Location (UCSC)Chr 10:
120.34 - 120.34 Mb		Chr 19:
60.52 - 60.52 Mb
PubMed search[1][2]

The prolactin-releasing hormone receptor (PRRP) is a G-protein coupled receptor[1] that binds the prolactin releasing hormone.[2]

PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002).[supplied by OMIM][3]

References

  1. ^ Marchese A, Heiber M, Nguyen T, Heng HH, Saldivia VR, Cheng R, Murphy PM, Tsui LC, Shi X, Gregor P (1995). [Expression error: Missing operand for > "Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors"]. Genomics 29 (2): 335–44. doi:10.1006/geno.1995.9996. PMID 8666380. 
  2. ^ Hinuma S, Habata Y, Fujii R, Kawamata Y, Hosoya M, Fukusumi S, Kitada C, Masuo Y, Asano T, Matsumoto H, Sekiguchi M, Kurokawa T, Nishimura O, Onda H, Fujino M (1998). [Expression error: Missing operand for > "A prolactin-releasing peptide in the brain"]. Nature 393 (6682): 272–6. doi:10.1038/30515. PMID 9607765. 
  3. ^ "Entrez Gene: PRLHR prolactin releasing hormone receptor". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2834. 

Further reading

  • Hinuma S, Onda H, Fujino M (1999). [Expression error: Missing operand for > "The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors."]. J. Mol. Med. 77 (6): 495–504. doi:10.1007/s001090050403. PMID 10475064. 
  • Marchese A, Heiber M, Nguyen T, et al. (1996). [Expression error: Missing operand for > "Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors."]. Genomics 29 (2): 335–44. PMID 8666380. 
  • Hinuma S, Habata Y, Fujii R, et al. (1998). [Expression error: Missing operand for > "A prolactin-releasing peptide in the brain."]. Nature 393 (6682): 272–6. doi:10.1038/30515. PMID 9607765. 
  • Fujii R, Fukusumi S, Hosoya M, et al. (1999). [Expression error: Missing operand for > "Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor."]. Regul. Pept. 83 (1): 1–10. doi:10.1016/S0167-0115(99)00028-2. PMID 10498338. 
  • Langmead CJ, Szekeres PG, Chambers JK, et al. (2000). [Expression error: Missing operand for > "Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor."]. Br. J. Pharmacol. 131 (4): 683–8. doi:10.1038/sj.bjp.0703617. PMID 11030716. 
  • Lin SH, Arai AC, Wang Z, et al. (2001). [Expression error: Missing operand for > "The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering."]. Mol. Pharmacol. 60 (5): 916–23. PMID 11641419. 
  • Ozawa A, Yamada M, Satoh T, et al. (2002). [Expression error: Missing operand for > "Transcriptional regulation of the human PRL-releasing peptide (PrRP) receptor gene by a dopamine 2 Receptor agonist: cloning and characterization of the human PrRP receptor gene and its promoter region."]. Mol. Endocrinol. 16 (4): 785–98. doi:10.1210/me.16.4.785. PMID 11923475. 
  • Takahashi K, Totsune K, Murakami O, et al. (2003). [Expression error: Missing operand for > "Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of adrenocortical tumors, pheochromocytomas and neuroblastomas."]. Peptides 23 (6): 1135–40. doi:10.1016/S0196-9781(02)00046-3. PMID 12126742. 
  • Kemp DM, Lin JC, Ubeda M, Habener JF (2002). [Expression error: Missing operand for > "NRSF/REST confers transcriptional repression of the GPR10 gene via a putative NRSE/RE-1 located in the 5' promoter region."]. FEBS Lett. 531 (2): 193–8. doi:10.1016/S0014-5793(02)03502-0. PMID 12417311. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). [Expression error: Missing operand for > "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."]. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Bhattacharyya S, Luan J, Challis B, et al. (2003). [Expression error: Missing operand for > "Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population."]. Diabetes 52 (5): 1296–9. doi:10.2337/diabetes.52.5.1296. PMID 12716769. 
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). [Expression error: Missing operand for > "The DNA sequence and comparative analysis of human chromosome 10."]. Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). [Expression error: Missing operand for > "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."]. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ellacott KL, Donald EL, Clarkson P, et al. (2005). [Expression error: Missing operand for > "Characterization of a naturally-occurring polymorphism in the UHR-1 gene encoding the putative rat prolactin-releasing peptide receptor."]. Peptides 26 (4): 675–81. doi:10.1016/j.peptides.2004.11.020. PMID 15752583. 
  • Lagerström MC, Fredriksson R, Bjarnadóttir TK, et al. (2005). [Expression error: Missing operand for > "Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution."]. Genomics 85 (6): 688–703. doi:10.1016/j.ygeno.2005.02.007. PMID 15885496. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). [Expression error: Missing operand for > "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes."]. Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 

External links

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

v • d • e
Transmembrane receptor: G protein-coupled receptors
Class A: Rhodopsin like
α1 (A, B, D) · α2 (A, B, C) · β1 · β2 · β3
CysLT (1, 2) · LTB4 (1, 2) · FPRL1 · OXE · Prostaglandin (DP (1, 2), EP (1, 2, 3, 4), FP) · Prostacyclin · Thromboxane
B/W (1, 2) · FF (1, 2) · S · Y (1, 2, 4, 5) · Neuromedin (B, U (1, 2)) · Neurotensin (1, 2)
GPR (1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 82, 83, 84, 85, 87, 88, 92, 101, 103, 109A, 109B, 119, 120, 132, 135, 137B, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 173, 174, 176, 177, 182)
Adenosine (A1, A2A, A2B, A3) · P2Y (1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14)
(all but 5-HT3) 5-HT1 (A, B, D, E, F) · 5-HT2 (A, B, C) · 5-HT (4, 5A, 6, 7)
Other
Acetylcholine (M1, M2, M3, M4, M5) · Adrenomedullin · Anaphylatoxin (C3a, C5a) · Angiotensin (1, 2) · Apelin · Bile acid · Bombesin (BRS3, GRPR, NMBR) · Bradykinin (B1, B2) · Cannabinoid (CB1, CB2) · Chemokine · Cholecystokinin (A, B) · Dopamine (D1, D2, D3, D4, D5) · EBI2 · Endothelin (A, B) · Estrogen · Formyl peptide (1, 2, 3) · Free fatty acid (1, 2, 3, 4) · FSH · Galanin (1, 2, 3) · Gonadotropin-releasing hormone (1, 2) · GHB receptor · Ghrelin · Histamine (H1, H2, H3, H4) · Kisspeptin · Luteinizing hormone/choriogonadotropin · lysophosphatidic acid (1, 2, 3, 4, 5, 6)  · Lysophospholipid (1, 2, 3, 4, 5, 6, 7, 8) · MAS (1, 1L, D, E, F, G, X1, X2, X3, X4) · Melanocortin (1, 2, 3, 4, 5) · MCHR (1, 2) · Melatonin (1A, 1B, 1C) · Niacin (1, 2) · Motilin · Opioid (Delta, Kappa, Mu, Nociceptin & Zeta, but not Sigma) · Olfactory · Opsin (3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH) · Orexin (1, 2) · Oxytocin · Oxoglutarate · PAF · Prokineticin (1, 2) · Prolactin-releasing peptide · Protease-activated (1, 2, 3, 4) · Relaxin (1, 2, 3, 4) · Somatostatin (1, 2, 3, 4, 5) · Sphingosine-1-phosphate (1, 2, 3, 4, 5) · SREB · Succinate · TAAR (1, 2, 3, 5, 6, 8, 9) · Tachykinin (1, 2, 3) · Thyrotropin · Thyrotropin-releasing hormone · Urotensin-II · Vasopressin (1A, 1B, 2)
Class B: Secretin like
GPR (56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 157)
Other
Class C: Metabotropic
glutamate / pheromone
TAS1R (1, 2, 3) · TAS2R (1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 38, 39, 40, 41, 43, 44, 45, 46, 47, 48, 49, 50)
Other
Frizzled / Smoothened
Frizzled (1, 2, 3, 4, 5, 6, 7, 8, 9, 10) · Smoothened

 

All translations of Prolactin-releasing_peptide_receptor


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