SLC10A2
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| Solute carrier family 10 (sodium/bile acid cotransporter family), member 2 | |||||||||||
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| Identifiers | |||||||||||
| Symbols | SLC10A2; ASBT; ISBT; NTCP2 | ||||||||||
| External IDs | OMIM: 601295 MGI: 1201406 HomoloGene: 390 GeneCards: SLC10A2 Gene | ||||||||||
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| RNA expression pattern | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 6555 | 20494 | |||||||||
| Ensembl | ENSG00000125255 | ENSMUSG00000023073 | |||||||||
| UniProt | Q12908 | Q0VBB8 | |||||||||
| RefSeq (mRNA) | NM_000452 | NM_011388 | |||||||||
| RefSeq (protein) | NP_000443 | NP_035518 | |||||||||
| Location (UCSC) | Chr 13: 102.49 - 102.52 Mb | Chr 8: 5.09 - 5.11 Mb | |||||||||
| PubMed search | [1] | [2] | |||||||||
Ileal sodium/bile acid cotransporter is a protein that in humans is encoded by the SLC10A2 gene.[1][2]
See also
References
- ^ Wong MH, Rao PN, Pettenati MJ, Dawson PA (Sep 1996). [Expression error: Missing operand for > "Localization of the ileal sodium-bile acid cotransporter gene (SLC10A2) to human chromosome 13q33"]. Genomics 33 (3): 538-40. doi:. PMID 8661017.
- ^ "Entrez Gene: SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6555.
Further reading
- Shneider BL (2001). [Expression error: Missing operand for > "Intestinal bile acid transport: biology, physiology, and pathophysiology."]. J. Pediatr. Gastroenterol. Nutr. 32 (4): 407–17. doi:. PMID 11396803.
- Balakrishnan A, Polli JE (2006). [Expression error: Missing operand for > "Apical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug target."]. Mol. Pharm. 3 (3): 223–30. doi:. PMID 16749855.
- Wong MH, Oelkers P, Dawson PA (1995). [Expression error: Missing operand for > "Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity."]. J. Biol. Chem. 270 (45): 27228–34. doi:. PMID 7592981.
- Oelkers P, Kirby LC, Heubi JE, Dawson PA (1997). [Expression error: Missing operand for > "Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)."]. J. Clin. Invest. 99 (8): 1880–7. doi:. PMID 9109432.
- Craddock AL, Love MW, Daniel RW, et al. (1998). [Expression error: Missing operand for > "Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter."]. Am. J. Physiol. 274 (1 Pt 1): G157–69. PMID 9458785.
- Montagnani M, Love MW, Rössel P, et al. (2002). [Expression error: Missing operand for > "Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption."]. Scand. J. Gastroenterol. 36 (10): 1077–80. doi:. PMID 11589382.
- Love MW, Craddock AL, Angelin B, et al. (2002). [Expression error: Missing operand for > "Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia."]. Arterioscler. Thromb. Vasc. Biol. 21 (12): 2039–45. doi:. PMID 11742882.
- Jung D, Fried M, Kullak-Ublick GA (2002). [Expression error: Missing operand for > "Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha."]. J. Biol. Chem. 277 (34): 30559–66. doi:. PMID 12055195.
- Zelcer N, Saeki T, Bot I, et al. (2003). [Expression error: Missing operand for > "Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter."]. Biochem. J. 369 (Pt 1): 23–30. doi:. PMID 12220224.
- Chumakov I, Blumenfeld M, Guerassimenko O, et al. (2002). [Expression error: Missing operand for > "Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia."]. Proc. Natl. Acad. Sci. U.S.A. 99 (21): 13675–80. doi:. PMID 12364586.
- Dunham A, Matthews LH, Burton J, et al. (2004). [Expression error: Missing operand for > "The DNA sequence and analysis of human chromosome 13."]. Nature 428 (6982): 522–8. doi:. PMID 15057823.
- Neimark E, Chen F, Li X, Shneider BL (2004). [Expression error: Missing operand for > "Bile acid-induced negative feedback regulation of the human ileal bile acid transporter."]. Hepatology 40 (1): 149–56. doi:. PMID 15239098.
- Xia X, Roundtree M, Merikhi A, et al. (2004). [Expression error: Missing operand for > "Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes."]. J. Biol. Chem. 279 (43): 44931–7. doi:. PMID 15304498.
- Zhang EY, Phelps MA, Banerjee A, et al. (2004). [Expression error: Missing operand for > "Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2)."]. Biochemistry 43 (36): 11380–92. doi:. PMID 15350125.
- Banerjee A, Ray A, Chang C, Swaan PW (2005). [Expression error: Missing operand for > "Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2)."]. Biochemistry 44 (24): 8908–17. doi:. PMID 15952798.
- Nakahara M, Furuya N, Takagaki K, et al. (2006). [Expression error: Missing operand for > "Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine."]. J. Biol. Chem. 280 (51): 42283–9. doi:. PMID 16230354.
- Bergheim I, Harsch S, Mueller O, et al. (2006). [Expression error: Missing operand for > "Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers."]. J. Lipid Res. 47 (1): 42–50. doi:. PMID 16237211.
- Banerjee A, Swaan PW (2006). [Expression error: Missing operand for > "Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains."]. Biochemistry 45 (3): 943–53. doi:. PMID 16411770.
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