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Wikipedia

SLC10A2

From Wikipedia, the free encyclopedia

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Solute carrier family 10 (sodium/bile acid cotransporter family), member 2
Identifiers
SymbolsSLC10A2; ASBT; ISBT; NTCP2
External IDsOMIM601295 MGI1201406 HomoloGene390 GeneCards: SLC10A2 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez655520494
EnsemblENSG00000125255ENSMUSG00000023073
UniProtQ12908Q0VBB8
RefSeq (mRNA)NM_000452NM_011388
RefSeq (protein)NP_000443NP_035518
Location (UCSC)Chr 13:
102.49 - 102.52 Mb
Chr 8:
5.09 - 5.11 Mb
PubMed search[1][2]

Ileal sodium/bile acid cotransporter is a protein that in humans is encoded by the SLC10A2 gene.[1][2]


See also

References

  1. ^ Wong MH, Rao PN, Pettenati MJ, Dawson PA (Sep 1996). [Expression error: Missing operand for > "Localization of the ileal sodium-bile acid cotransporter gene (SLC10A2) to human chromosome 13q33"]. Genomics 33 (3): 538-40. doi:10.1006/geno.1996.0233. PMID 8661017. 
  2. ^ "Entrez Gene: SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6555. 

Further reading

  • Shneider BL (2001). [Expression error: Missing operand for > "Intestinal bile acid transport: biology, physiology, and pathophysiology."]. J. Pediatr. Gastroenterol. Nutr. 32 (4): 407–17. doi:10.1097/00005176-200104000-00002. PMID 11396803. 
  • Balakrishnan A, Polli JE (2006). [Expression error: Missing operand for > "Apical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug target."]. Mol. Pharm. 3 (3): 223–30. doi:10.1021/mp060022d. PMID 16749855. 
  • Wong MH, Oelkers P, Dawson PA (1995). [Expression error: Missing operand for > "Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity."]. J. Biol. Chem. 270 (45): 27228–34. doi:10.1074/jbc.270.45.27228. PMID 7592981. 
  • Oelkers P, Kirby LC, Heubi JE, Dawson PA (1997). [Expression error: Missing operand for > "Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)."]. J. Clin. Invest. 99 (8): 1880–7. doi:10.1172/JCI119355. PMID 9109432. 
  • Craddock AL, Love MW, Daniel RW, et al. (1998). [Expression error: Missing operand for > "Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter."]. Am. J. Physiol. 274 (1 Pt 1): G157–69. PMID 9458785. 
  • Montagnani M, Love MW, Rössel P, et al. (2002). [Expression error: Missing operand for > "Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption."]. Scand. J. Gastroenterol. 36 (10): 1077–80. doi:10.1080/003655201750422693. PMID 11589382. 
  • Love MW, Craddock AL, Angelin B, et al. (2002). [Expression error: Missing operand for > "Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia."]. Arterioscler. Thromb. Vasc. Biol. 21 (12): 2039–45. doi:10.1161/hq1201.100262. PMID 11742882. 
  • Jung D, Fried M, Kullak-Ublick GA (2002). [Expression error: Missing operand for > "Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha."]. J. Biol. Chem. 277 (34): 30559–66. doi:10.1074/jbc.M203511200. PMID 12055195. 
  • Zelcer N, Saeki T, Bot I, et al. (2003). [Expression error: Missing operand for > "Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter."]. Biochem. J. 369 (Pt 1): 23–30. doi:10.1042/BJ20021081. PMID 12220224. 
  • Chumakov I, Blumenfeld M, Guerassimenko O, et al. (2002). [Expression error: Missing operand for > "Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia."]. Proc. Natl. Acad. Sci. U.S.A. 99 (21): 13675–80. doi:10.1073/pnas.182412499. PMID 12364586. 
  • Dunham A, Matthews LH, Burton J, et al. (2004). [Expression error: Missing operand for > "The DNA sequence and analysis of human chromosome 13."]. Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823. 
  • Neimark E, Chen F, Li X, Shneider BL (2004). [Expression error: Missing operand for > "Bile acid-induced negative feedback regulation of the human ileal bile acid transporter."]. Hepatology 40 (1): 149–56. doi:10.1002/hep.20295. PMID 15239098. 
  • Xia X, Roundtree M, Merikhi A, et al. (2004). [Expression error: Missing operand for > "Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes."]. J. Biol. Chem. 279 (43): 44931–7. doi:10.1074/jbc.M400969200. PMID 15304498. 
  • Zhang EY, Phelps MA, Banerjee A, et al. (2004). [Expression error: Missing operand for > "Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2)."]. Biochemistry 43 (36): 11380–92. doi:10.1021/bi049270a. PMID 15350125. 
  • Banerjee A, Ray A, Chang C, Swaan PW (2005). [Expression error: Missing operand for > "Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2)."]. Biochemistry 44 (24): 8908–17. doi:10.1021/bi050553s. PMID 15952798. 
  • Nakahara M, Furuya N, Takagaki K, et al. (2006). [Expression error: Missing operand for > "Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine."]. J. Biol. Chem. 280 (51): 42283–9. doi:10.1074/jbc.M507454200. PMID 16230354. 
  • Bergheim I, Harsch S, Mueller O, et al. (2006). [Expression error: Missing operand for > "Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers."]. J. Lipid Res. 47 (1): 42–50. doi:10.1194/jlr.M500215-JLR200. PMID 16237211. 
  • Banerjee A, Swaan PW (2006). [Expression error: Missing operand for > "Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains."]. Biochemistry 45 (3): 943–53. doi:10.1021/bi052202j. PMID 16411770. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

 

All translations of SLC10A2


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