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BoggleSLC36A1
From Wikipedia, the free encyclopedia
| edit |
| Solute carrier family 36 (proton/amino acid symporter), member 1 | |||
|---|---|---|---|
| Identifiers | |||
| Symbols | SLC36A1; PAT1; LYAAT1; TRAMD3 | ||
| External IDs | OMIM: 606561 MGI: 2445299 HomoloGene: 70571 GeneCards: SLC36A1 Gene | ||
| RNA expression pattern | |||
| More reference expression data | |||
| Orthologs | |||
| Species | Human | Mouse | |
| Entrez | 206358 | 215335 | |
| Ensembl | ENSG00000123643 | ENSMUSG00000020261 | |
| UniProt | Q7Z2H8 | Q5F227 | |
| RefSeq (mRNA) | NM_078483 | NM_153139 | |
| RefSeq (protein) | NP_510968 | NP_694779 | |
| Location (UCSC) | Chr 5: 150.81 - 150.85 Mb | Chr 11: 55.05 - 55.08 Mb | |
| PubMed search | [1] | [2] | |
Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene.[1][2][3]
This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.[3]
See also
References
- ^ Boll M, Foltz M, Rubio-Aliaga I, Kottra G, Daniel H (Jun 2002). [Expression error: Missing operand for > "Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters"]. J Biol Chem 277 (25): 22966-73. doi:. PMID 11959859.
- ^ Sagne C, Agulhon C, Ravassard P, Darmon M, Hamon M, El Mestikawy S, Gasnier B, Giros B (Jun 2001). [Expression error: Missing operand for > "Identification and characterization of a lysosomal transporter for small neutral amino acids"]. Proc Natl Acad Sci U S A 98 (13): 7206-11. doi:. PMID 11390972.
- ^ a b "Entrez Gene: SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=206358.
Further reading
- Hartley JL, Temple GF, Brasch MA (2001). [Expression error: Missing operand for > "DNA cloning using in vitro site-specific recombination."]. Genome Res. 10 (11): 1788–95. doi:. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). [Expression error: Missing operand for > "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."]. Genome Res. 11 (3): 422–35. doi:. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). [Expression error: Missing operand for > "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing."]. EMBO Rep. 1 (3): 287–92. doi:. PMID 11256614.
- Chen Z, Fei YJ, Anderson CM, et al. (2003). [Expression error: Missing operand for > "Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2."]. J. Physiol. (Lond.) 546 (Pt 2): 349–61. doi:. PMID 12527723.
- Wreden CC, Johnson J, Tran C, et al. (2003). [Expression error: Missing operand for > "The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons."]. J. Neurosci. 23 (4): 1265–75. PMID 12598615.
- Boll M, Foltz M, Rubio-Aliaga I, Daniel H (2004). [Expression error: Missing operand for > "A cluster of proton/amino acid transporter genes in the human and mouse genomes."]. Genomics 82 (1): 47–56. doi:. PMID 12809675.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). [Expression error: Missing operand for > "Complete sequencing and characterization of 21,243 full-length human cDNAs."]. Nat. Genet. 36 (1): 40–5. doi:. PMID 14702039.
- Bermingham JR, Pennington J (2004). [Expression error: Missing operand for > "Organization and expression of the SLC36 cluster of amino acid transporter genes."]. Mamm. Genome 15 (2): 114–25. doi:. PMID 15058382.
- Wiemann S, Arlt D, Huber W, et al. (2004). [Expression error: Missing operand for > "From ORFeome to biology: a functional genomics pipeline."]. Genome Res. 14 (10B): 2136–44. doi:. PMID 15489336.
- Anderson CM, Grenade DS, Boll M, et al. (2004). [Expression error: Missing operand for > "H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat."]. Gastroenterology 127 (5): 1410–22. doi:. PMID 15521011.
- Anderson CM, Thwaites DT (2005). [Expression error: Missing operand for > "Indirect regulation of the intestinal H+-coupled amino acid transporter hPAT1 (SLC36A1)."]. J. Cell. Physiol. 204 (2): 604–13. doi:. PMID 15754324.
- Abbot EL, Grenade DS, Kennedy DJ, et al. (2006). [Expression error: Missing operand for > "Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1."]. Br. J. Pharmacol. 147 (3): 298–306. doi:. PMID 16331283.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). [Expression error: Missing operand for > "The LIFEdb database in 2006."]. Nucleic Acids Res. 34 (Database issue): D415–8. doi:. PMID 16381901.
- Kuan YH, Gruebl T, Soba P, et al. (2007). [Expression error: Missing operand for > "PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2."]. J. Biol. Chem. 281 (52): 40114–23. doi:. PMID 17050537.
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