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definitions
scleritis (n.)
1.inflammation of the sclera
Scleritis (n.)
1.(MeSH)Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
Merriam Webster
Scleritis‖Scle*ri"tis (skl�*rī"tĭs), n. [NL.] See Sclerotitis.
synonyms
Scleritis (n.) (MeSH)
phrases
Necrotizing Scleritis • Scleritis and episcleritis in diseases classified elsewhere • Zoster scleritis
analogical dictionary
inflammation; redness; rubor[ClasseHyper.]
symptom[Hyper.]
enflammer (fr)[Nominalisation]
inflame - inflame - crimson, flushed, red, reddened, red-faced[Dérivé]
inflammatory disease[Desc]
inflammation, redness, rubor[Hyper.]
scleritis (n.)
Wikipedia
Scleritis
 |
This article includes a list of references, but its sources remain unclear because it has insufficient inline citations. (May 2012) |
Scleritis: inflammation of entire thickness of the sclera.
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This article needs additional citations for verification. (January 2011) |
| Scleritis | |
|---|---|
| Classification and external resources | |
| ICD-10 | H15.0 |
| ICD-9 | 379.0 |
| DiseasesDB | 11898 |
| MedlinePlus | 001003 scleritis. 001019 episcleritis |
| eMedicine | emerg/521 oph/642 |
| MeSH | D015423 |
Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera. The disease is often contracted through association with other diseases of the body, such as Wegener's granulomatosis or rheumatoid arthritis; it can also be attained through disorders of menstruation. For this reason, scleritis occurs frequently among young women. There are three types of scleritis: diffuse scleritis (the most common), nodular scleritis, and necrotizing scleritis (the most severe). Scleritis may be the first symptom of onset of connective tissue disease[1].
Episcleritis is inflammation of the episclera, a less serious condition that seldom develops into scleritis.[1]
Contents |
Signs and symptoms
Symptoms of the disease include:[2]
- Redness of the sclera and conjunctiva, sometimes changing to a purple hue
- Severe ocular pain (not present in episcleritis) which may radiate to the temple or jaw
- Photophobia and tearing
- Decrease in visual acuity, possibly leading to blindness
Diagnosis
Scleritis is best detected by examining the sclera in daylight; retracting the lids helps determine the extent of involvement. Other aspects of the eye exam (i.e. visual acuity testing, slit lamp examination, etc.) can be normal. Ancillary tests CT scans, MRIs, and ultrasonographies can be helpful, but do not replace the physical examination.
Treatment
In very severe cases of necrotizing scleritis, eye surgery must be performed to repair damaged corneal tissue in the eye and preserve the patient's vision. For less severe cases, nonsteroidal anti-inflammatory drugs, such as ibuprofen, are prescribed for pain relief. Scleritis itself is treated with an oral medication containing corticosteroids and an eye solution. In some cases, antibiotics are prescribed. Simply using eye drops will not treat scleritis. In more aggressive cases of scleritis, chemotherapy (such as systemic immunosuppressive therapy with such drugs as cyclophosphamide or azathioprine) may be used to treat the disease. If not treated, scleritis can cause blindness.
External links
End Notes
- ^ "Episcleritis: MedlinePlus Medical Encyclopedia". Bethesda, MD: United States National Library of Medicine. http://www.nlm.nih.gov/medlineplus/ency/article/001019.htm. Retrieved 20 June 2010.
- ^ Vorvick, Linda J., M.D. (Reviewer) (July 28, 2010, Review date). "Scleritis". Pub Med Health. United States National Library of Medicine. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001998/. Retrieved July 6, 2011.
References
- Sainz de la Maza, Maite, MD, PhD "Scleritis", eMedicine.com, September 26, 2006. Accessed June 12, 2007.
- Goldstein DA, Tessler HH. Episcleritis and scleritis. In: Yanoff M, Duker JS, eds. Ophthalmology. 3rd ed. St. Louis, Mo: Mosby Elsevier; 2008:chap 4.11.
- Rosenbaum JT. The Eye and rheumatic diseases. In: Firestein GS, Budd RC, Harris ED Jr, et al., eds. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 46.
- Watson P. Diseases of the sclera and episclera. In: Tasman W, Jaeger EA, eds. Duane’s Ophthalmology. 15th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2009:chap 23.
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