1.(MeSH)A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.
D12.644.360.225.200, D12.722.214.171.124, D12.776.476.225.200, D12.776.624.776.355.200, Cdk4-Associated Protein p16 (MeSH), CDKN2A Protein (MeSH), CDKN2 Protein (MeSH), Cyclin-Dependent Kinase Inhibitor-2A (MeSH), Cyclin-Dependent Kinase Inhibitor p16 (MeSH), INK4A Protein (MeSH), MTS1 Protein (MeSH), Multiple Tumor Suppressor-1 (MeSH), p16INK4A Protein (MeSH), p16INK4 Protein (MeSH)
Intracellular Signaling Peptides, Intracellular Signaling Peptides and Proteins, Intracellular Signaling Proteins - cdc Proteins, Cell Cycle Proteins, Cell-Cycle Regulatory Proteins, Cell Division Cycle Proteins - Growth Suppressor Proteins, Metastasis Suppressor Proteins, Tumor Suppressor Proteins[Hyper.]
CDKI Proteins, CIP-KIP CDKI Proteins, CIP-KIP CKI Proteins, CIP-KIP Cyclin-Dependent Kinase Inhibitors, CKI Proteins, Cyclin-Dependent Kinase Inhibitor Proteins, Cyclin-Kinase Inhibitor Proteins, Inhibitors of Cyclin-Dependent Kinase 4 Proteins, INK4 CDKI Proteins, INK4 CKI Proteins, INK4 Cyclin-Dependent Kinase Inhibitors[Hyper.]
p16(INK4A) (n.) [MeSH]
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